Adult neural stem cell fate is determined by thyroid hormone activation of mitochondrial metabolism

OBJECTIVE: In the adult brain, neural stem cells (NSCs) located in the subventricular zone (SVZ) produce both neuronal and glial cells. Thyroid hormones (THs) regulate adult NSC differentiation towards a neuronal phenotype, but also have major roles in mitochondrial metabolism. As NSC metabolism rel...

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Detalles Bibliográficos
Autores principales: Gothié, J.D., Sébillot, A., Luongo, C., Legendre, M., Nguyen Van, C., Le Blay, K., Perret-Jeanneret, M., Remaud, S., Demeneix, B.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681236/
https://www.ncbi.nlm.nih.gov/pubmed/29107300
http://dx.doi.org/10.1016/j.molmet.2017.08.003

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