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Deletion of hepatic carbohydrate response element binding protein (ChREBP) impairs glucose homeostasis and hepatic insulin sensitivity in mice

OBJECTIVE: Carbohydrate response element binding protein (ChREBP) is a transcription factor that responds to glucose and activates genes involved in the glycolytic and lipogenic pathways. Recent studies have linked adipose ChREBP to insulin sensitivity in mice. However, while ChREBP is most highly e...

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Detalles Bibliográficos
Autores principales:	Jois, Tara, Chen, Weiyi, Howard, Victor, Harvey, Rebecca, Youngs, Kristina, Thalmann, Claudia, Saha, Pradip, Chan, Lawrence, Cowley, Michael A., Sleeman, Mark W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681238/ https://www.ncbi.nlm.nih.gov/pubmed/29107286 http://dx.doi.org/10.1016/j.molmet.2017.07.006

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