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Identification of islet-enriched long non-coding RNAs contributing to β-cell failure in type 2 diabetes
OBJECTIVE: Non-coding RNAs constitute a major fraction of the β-cell transcriptome. While the involvement of microRNAs is well established, the contribution of long non-coding RNAs (lncRNAs) in the regulation of β-cell functions and in diabetes development remains poorly understood. The aim of this...
Autores principales: | Motterle, Anna, Gattesco, Sonia, Peyot, Marie-Line, Esguerra, Jonathan Lou S., Gomez-Ruiz, Ana, Laybutt, D. Ross, Gilon, Patrick, Burdet, Frédéric, Ibberson, Mark, Eliasson, Lena, Prentki, Marc, Regazzi, Romano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681241/ https://www.ncbi.nlm.nih.gov/pubmed/29107288 http://dx.doi.org/10.1016/j.molmet.2017.08.005 |
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