Cargando…

Evaluating the glucose raising effect of established loci via a genetic risk score

Recent genome-wide association studies have identified several single nucleotide polymorphisms (SNPs) associated with glucose levels. We tested the hypothesis here whether the cumulative effect of glucose raising SNPs, assessed via a score, is associated with glucose levels. A total of 1,434 partici...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marouli, Eirini, Kanoni, Stavroula, Mamakou, Vasiliki, Hackinger, Sophie, Southam, Lorraine, Prins, Bram, Rentari, Angela, Dimitriou, Maria, Zengini, Eleni, Gonidakis, Fragiskos, Kolovou, Genovefa, Kontaxakis, Vassilis, Rallidis, Loukianos, Tentolouris, Nikolaos, Thanopoulou, Anastasia, Lamnissou, Klea, Dedoussis, George, Zeggini, Eleftheria, Deloukas, Panagiotis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681259/ https://www.ncbi.nlm.nih.gov/pubmed/29125842 http://dx.doi.org/10.1371/journal.pone.0186669

Ejemplares similares

Evidence for genetic contribution to the increased risk of type 2 diabetes in schizophrenia
por: Hackinger, Sophie, et al.
Publicado: (2018)

Combination therapy as a potential risk factor for the development of type 2 diabetes in patients with schizophrenia: the GOMAP study
por: Mamakou, Vasiliki, et al.
Publicado: (2018)

A Posteriori Dietary Patterns and Coronary Artery Disease in a Greek Case–Control Study
por: Dimitriou, Maria, et al.
Publicado: (2023)

Robust Bioinformatics Approaches Result in the First Polygenic Risk Score for BMI in Greek Adults
por: Kafyra, Maria, et al.
Publicado: (2023)

Statistical methods to detect pleiotropy in human complex traits
por: Hackinger, Sophie, et al.
Publicado: (2017)

A Dietary Pattern with High Sugar Content Is Associated with Cardiometabolic Risk Factors in the Pomak Population
por: Farmaki, Aliki-Eleni, et al.
Publicado: (2019)

A novel variant in GLIS3 is associated with osteoarthritis
por: Casalone, Elisabetta, et al.
Publicado: (2018)

Exercise dependence and orthorexia nervosa in Crossfit: exploring the role of perfectionism
por: Mavrandrea, Panagiota, et al.
Publicado: (2022)

Replication of Established Common Genetic Variants for Adult BMI and Childhood Obesity in Greek Adolescents: The TEENAGE Study
por: Ntalla, Ioanna, et al.
Publicado: (2013)

Very low-depth sequencing in a founder population identifies a cardioprotective APOC3 signal missed by genome-wide imputation
por: Gilly, Arthur, et al.
Publicado: (2016)

A zebrafish forward genetic screen identifies an indispensable threonine residue in the kinase domain of PRKD2
por: Giardoglou, Panagiota, et al.
Publicado: (2021)

ST-elevation myocardial infarction in a 39-year-old patient with “normal” coronary arteries as a thrombotic complication of COVID-19
por: Liori, Sotiria, et al.
Publicado: (2021)

Lipoprotein(a): Its Association with Calcific Aortic Valve Stenosis, the Emerging RNA-Related Treatments and the Hope for a New Era in “Treating” Aortic Valve Calcification
por: Tsamoulis, Donatos, et al.
Publicado: (2023)

An ominous triad: acute inferior ST-segment elevation myocardial infarction, right ventricular infarction, and ventricular septal rupture/dissection
por: Rallidis, Loukianos S, et al.
Publicado: (2023)

A 12-month study of dialectical behavioral therapy for bοrderline patients suffering from eating disorders
por: Liakopoulou, Efi, et al.
Publicado: (2023)

Widespread epigenomic, transcriptomic and proteomic differences between hip osteophytic and articular chondrocytes in osteoarthritis
por: Steinberg, Julia, et al.
Publicado: (2018)

Assessment of the Validity and Reproducibility of a Novel Standardized Test Meal for the Study of Postprandial Triacylglycerol Concentrations
por: Tentolouris, Nikolaos, et al.
Publicado: (2017)

Erratum to: Assessment of the Validity and Reproducibility of a Novel Standardized Test Meal for the Study of Postprandial Triacylglycerol Concentrations
por: Tentolouris, Nikolaos, et al.
Publicado: (2017)

Pathways to understanding the genomic aetiology of osteoarthritis
por: Cibrián Uhalte, Elena, et al.
Publicado: (2017)

Lipidomics in vascular health: current perspectives
por: Kolovou, Genovefa, et al.
Publicado: (2015)

Volanesorsen: A New Era in the Treatment of Severe Hypertriglyceridemia
por: Kolovou, Genovefa, et al.
Publicado: (2022)

Is pulmonary arterial hypertension associated with interferon-β therapy for multiple sclerosis reversible? A case study to explore the complexity
por: Anthi, Anastasia, et al.
Publicado: (2020)

Prevalence of Diabetes and Its Association with Atherosclerotic Cardiovascular Disease Risk in Patients with Familial Hypercholesterolemia: An Analysis from the Hellenic Familial Hypercholesterolemia Registry (HELLAS-FH)
por: Boutari, Chrysoula, et al.
Publicado: (2022)

We Are Ageing
por: Kolovou, Genovefa D., et al.
Publicado: (2014)

Genetic Variant in the CYP19A1 Gene Associated with Coronary Artery Disease
por: Bampali, Konstantina, et al.
Publicado: (2015)

Rising trends in Takotsubo syndrome during the COVID-19 pandemic: A single center experience
por: Rallidis, Loukianos S., et al.
Publicado: (2022)

eNOS Gene Variants and the Risk of Premature Myocardial Infarction
por: Zigra, Aggeliki-Maria, et al.
Publicado: (2013)

Genetic characterization of Greek population isolates reveals strong genetic drift at missense and trait-associated variants
por: Panoutsopoulou, Kalliope, et al.
Publicado: (2014)

TM6SF2-rs58542926 Genetic Variant Modifies the Protective Effect of a “Prudent” Dietary Pattern on Serum Triglyceride Levels
por: Kalafati, Ioanna Panagiota, et al.
Publicado: (2023)

Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis
por: Zengini, Eleni, et al.
Publicado: (2018)

Radiographic endophenotyping in hip osteoarthritis improves the precision of genetic association analysis
por: Panoutsopoulou, Kalliope, et al.
Publicado: (2017)

Genome-wide meta-analysis of 92 cardiometabolic protein serum levels
por: Gilly, Arthur, et al.
Publicado: (2023)

Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits
por: Southam, Lorraine, et al.
Publicado: (2017)

One more look at guidelines for primary and secondary prevention of cardiovascular disease in women
por: Kolovou, Genovefa, et al.
Publicado: (2011)

Low-Dose Dobutamine Stress Echocardiography for the Early Detection of Pulmonary Arterial Hypertension in Selected Patients with Systemic Sclerosis Whose Resting Echocardiography Is Non-Diagnostic for Pulmonary Hypertension
por: Rallidis, Loukianos S., et al.
Publicado: (2021)

Whole-genome sequencing analysis of the cardiometabolic proteome
por: Gilly, Arthur, et al.
Publicado: (2020)

Non-traumatic and non-drug-induced rhabdomyolysis
por: Kolovou, Genovefa, et al.
Publicado: (2019)

Achieving low-density lipoprotein cholesterol targets as assessed by different methods in patients with familial hypercholesterolemia: an analysis from the HELLAS-FH registry
por: Rizos, Christos V., et al.
Publicado: (2020)

The Sphinx’s riddle: cardiovascular involvement in autoimmune rheumatic disease
por: Mavrogeni, Sophie, et al.
Publicado: (2016)

Endothelial nitric oxide synthase gene polymorphisms -786T >C and 894G >T in coronary artery bypass graft surgery patients
por: Ragia, Georgia, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_ojjprhbdmb37d7q4mvs7rifk0f