Maternal obesity alters fatty acid oxidation, AMPK activity, and associated DNA methylation in mesenchymal stem cells from human infants

OBJECTIVE: Infants born to mothers with obesity have greater adiposity, ectopic fat storage, and are at increased risk for childhood obesity and metabolic disease compared with infants of normal weight mothers, though the cellular mechanisms mediating these effects are unclear. METHODS: We tested th...

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Detalles Bibliográficos
Autores principales: Boyle, Kristen E., Patinkin, Zachary W., Shapiro, Allison L.B., Bader, Carly, Vanderlinden, Lauren, Kechris, Katerina, Janssen, Rachel C., Ford, Rebecca J., Smith, Brennan K., Steinberg, Gregory R., Davidson, Elizabeth J., Yang, Ivana V., Dabelea, Dana, Friedman, Jacob E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681274/
https://www.ncbi.nlm.nih.gov/pubmed/29107296
http://dx.doi.org/10.1016/j.molmet.2017.08.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681274/
https://www.ncbi.nlm.nih.gov/pubmed/29107296
http://dx.doi.org/10.1016/j.molmet.2017.08.012

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