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Novel essential amino acid-sulfanilamide hybrid as safe anti-ulcerogenic agent with anti-helicobacter pylori activity

A novel and safe essential amino acid (Leucine) incorporating sulfanilamide was synthesized, and evaluated for its anti-ulcerogenic activity and in vitro anti-Helicobacter pylori activity. The new molecule showed a dose dependent activity against absolute ethanol-induced ulcer in rats, it produced p...

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Detalles Bibliográficos
Autores principales: Awaad, Amani S., Alafeefy, Ahmed M., Alasmary, Fatmah A.S., El-Meligy, Reham M., Zain, M.E., Alqasoumi, Saleh I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681326/
https://www.ncbi.nlm.nih.gov/pubmed/29158702
http://dx.doi.org/10.1016/j.jsps.2017.02.012

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