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Cis-SNPs Set Testing and PrediXcan Analysis for Gene Expression Data using Linear Mixed Models

Understanding the functional mechanism of SNPs identified in GWAS on complex diseases is currently a challenging task. The studies of expression quantitative trait loci (eQTL) have shown that regulatory variants play a crucial role in the function of associated SNPs. Detecting significant genes (cal...

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Detalles Bibliográficos
Autores principales:	Zeng, Ping, Wang, Ting, Huang, Shuiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681585/ https://www.ncbi.nlm.nih.gov/pubmed/29127305 http://dx.doi.org/10.1038/s41598-017-15055-8

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