sPAGM: inferring subpathway activity by integrating gene and miRNA expression-robust functional signature identification for melanoma prognoses

MicroRNAs (miRNAs) regulate biological pathways by inhibiting gene expression. However, most current analytical methods fail to consider miRNAs, when inferring functional or pathway activities. In this study, we developed a model called sPAGM to infer subpathway activities by integrating gene and mi...

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Detalles Bibliográficos
Autores principales: Zhang, Chun-Long, Xu, Yan-Jun, Yang, Hai-Xiu, Xu, Ying-Qi, Shang, De-Si, Wu, Tan, Zhang, Yun-Peng, Li, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681640/
https://www.ncbi.nlm.nih.gov/pubmed/29127397
http://dx.doi.org/10.1038/s41598-017-15631-y

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