Nucleotide-Binding Oligomerization Domain 2 Contributes to Limiting Growth of Mycobacterium abscessus in the Lung of Mice by Regulating Cytokines and Nitric Oxide Production

Mycobacterium abscessus is a prominent cause of pulmonary infection in immunosuppressed patients and those with cystic fibrosis. Nucleotide-binding oligomerization domain (NOD) 2 is a cytosolic receptor which senses a bacterial peptidoglycan component, muramyl dipeptide (MDP). Although nucleotide-bi...

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Detalles Bibliográficos
Autores principales: Lee, Jun-Young, Lee, Moo-Seung, Kim, Dong-Jae, Yang, Soo-Jin, Lee, Sang-Jin, Noh, Eui-Jeong, Shin, Sung Jae, Park, Jong-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681718/
https://www.ncbi.nlm.nih.gov/pubmed/29163541
http://dx.doi.org/10.3389/fimmu.2017.01477

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