Interleukin 6 Present in Inflammatory Ascites from Advanced Epithelial Ovarian Cancer Patients Promotes Tumor Necrosis Factor Receptor 2-Expressing Regulatory T Cells

BACKGROUND: Epithelial ovarian cancer (EOC) remains a highly lethal gynecological malignancy. Ascites, an accumulation of peritoneal fluid present in one-third of patients at presentation, is linked to poor prognosis. High levels of regulatory T cells (Tregs) in ascites are correlated with tumor pro...

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Detalles Bibliográficos
Autores principales: Kampan, Nirmala Chandralega, Madondo, Mutsa Tatenda, McNally, Orla M., Stephens, Andrew N., Quinn, Michael A., Plebanski, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681739/
https://www.ncbi.nlm.nih.gov/pubmed/29163543
http://dx.doi.org/10.3389/fimmu.2017.01482

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