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The epidemiology of Norovirus in the Middle East and North Africa (MENA) region: a systematic review

Norovirus (NoV) is considered the second leading cause of viral acute gastroenteritis (AGE). To our knowledge, there are no systematic reviews assessing the role of NoV in AGE in the Middle East and North Africa (MENA) region. Consequently, we conducted an extensive systematic literature review on a...

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Autores principales: Kreidieh, Khalil, Charide, Rana, Dbaibo, Ghassan, Melhem, Nada M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681772/
https://www.ncbi.nlm.nih.gov/pubmed/29126448
http://dx.doi.org/10.1186/s12985-017-0877-3
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author Kreidieh, Khalil
Charide, Rana
Dbaibo, Ghassan
Melhem, Nada M.
author_facet Kreidieh, Khalil
Charide, Rana
Dbaibo, Ghassan
Melhem, Nada M.
author_sort Kreidieh, Khalil
collection PubMed
description Norovirus (NoV) is considered the second leading cause of viral acute gastroenteritis (AGE). To our knowledge, there are no systematic reviews assessing the role of NoV in AGE in the Middle East and North Africa (MENA) region. Consequently, we conducted an extensive systematic literature review on articles studying NoV in the 24 countries of the MENA region during the past 15 years (2000-2015). The methods and reporting were set according to the 2015 PRISMA-P and based on the elements from the international prospective register of systematic reviews (PROSPERO). We retrieved 38 studies meeting our predefined inclusion criteria and were used to extract full data. Studies reporting on NoV were conducted in 15 out of the 24 countries of the region. The reported NoV infection rates in MENA countries ranged between 0.82% and 36.84%. The majority of studies were clinical observational studies assessing NoV rates mainly among children. Participants were recruited from in- and outpatient clinics. NoV infection was reported all year round with with peaks observed mainly during cold months. GII.4 was the predominant genotype detected in stool of participants as reported by 16 out of 25 studies (64%). Overall, there is an increasing recognition of NoV as an important causative agent of AGE across all age groups in the MENA region. Further studies are needed to assess the national and the regional burden of NoV among different age groups, its molecular diversity and seasonal variability.
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spelling pubmed-56817722017-11-17 The epidemiology of Norovirus in the Middle East and North Africa (MENA) region: a systematic review Kreidieh, Khalil Charide, Rana Dbaibo, Ghassan Melhem, Nada M. Virol J Review Norovirus (NoV) is considered the second leading cause of viral acute gastroenteritis (AGE). To our knowledge, there are no systematic reviews assessing the role of NoV in AGE in the Middle East and North Africa (MENA) region. Consequently, we conducted an extensive systematic literature review on articles studying NoV in the 24 countries of the MENA region during the past 15 years (2000-2015). The methods and reporting were set according to the 2015 PRISMA-P and based on the elements from the international prospective register of systematic reviews (PROSPERO). We retrieved 38 studies meeting our predefined inclusion criteria and were used to extract full data. Studies reporting on NoV were conducted in 15 out of the 24 countries of the region. The reported NoV infection rates in MENA countries ranged between 0.82% and 36.84%. The majority of studies were clinical observational studies assessing NoV rates mainly among children. Participants were recruited from in- and outpatient clinics. NoV infection was reported all year round with with peaks observed mainly during cold months. GII.4 was the predominant genotype detected in stool of participants as reported by 16 out of 25 studies (64%). Overall, there is an increasing recognition of NoV as an important causative agent of AGE across all age groups in the MENA region. Further studies are needed to assess the national and the regional burden of NoV among different age groups, its molecular diversity and seasonal variability. BioMed Central 2017-11-10 /pmc/articles/PMC5681772/ /pubmed/29126448 http://dx.doi.org/10.1186/s12985-017-0877-3 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Kreidieh, Khalil
Charide, Rana
Dbaibo, Ghassan
Melhem, Nada M.
The epidemiology of Norovirus in the Middle East and North Africa (MENA) region: a systematic review
title The epidemiology of Norovirus in the Middle East and North Africa (MENA) region: a systematic review
title_full The epidemiology of Norovirus in the Middle East and North Africa (MENA) region: a systematic review
title_fullStr The epidemiology of Norovirus in the Middle East and North Africa (MENA) region: a systematic review
title_full_unstemmed The epidemiology of Norovirus in the Middle East and North Africa (MENA) region: a systematic review
title_short The epidemiology of Norovirus in the Middle East and North Africa (MENA) region: a systematic review
title_sort epidemiology of norovirus in the middle east and north africa (mena) region: a systematic review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681772/
https://www.ncbi.nlm.nih.gov/pubmed/29126448
http://dx.doi.org/10.1186/s12985-017-0877-3
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