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Production and purification of chimeric HBc virus-like particles carrying influenza virus LAH domain as vaccine candidates
BACKGROUND: The lack of a universal influenza vaccine is a global health problem. Interest is now focused on structurally conserved protein domains capable of eliciting protection against a broad range of influenza virus strains. The long alpha helix (LAH) is an attractive vaccine component since it...
Autores principales: | Kazaks, Andris, Lu, I-Na, Farinelle, Sophie, Ramirez, Alex, Crescente, Vincenzo, Blaha, Benjamin, Ogonah, Olotu, Mukhopadhyay, Tarit, de Obanos, Mapi Perez, Krimer, Alejandro, Akopjana, Inara, Bogans, Janis, Ose, Velta, Kirsteina, Anna, Kazaka, Tatjana, Stonehouse, Nicola J., Rowlands, David J., Muller, Claude P., Tars, Kaspars, Rosenberg, William M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681787/ https://www.ncbi.nlm.nih.gov/pubmed/29126399 http://dx.doi.org/10.1186/s12896-017-0396-8 |
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