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Reference-guided de novo assembly approach improves genome reconstruction for related species
BACKGROUND: The development of next-generation sequencing has made it possible to sequence whole genomes at a relatively low cost. However, de novo genome assemblies remain challenging due to short read length, missing data, repetitive regions, polymorphisms and sequencing errors. As more and more g...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681816/ https://www.ncbi.nlm.nih.gov/pubmed/29126390 http://dx.doi.org/10.1186/s12859-017-1911-6 |