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Evaluation of Alpha-1 Antitrypsin Levels and SERPINA1 Gene Polymorphisms in Sickle Cell Disease

Alpha-1 antitrypsin (AAT) is an inhibitor of neutrophil elastase and a member of the serine proteinase inhibitor (serpin) superfamily, and little is known about its activity in sickle cell disease (SCD). We hypothesize that AAT may undergo changes in SCD because of the high oxidative stress and infl...

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Detalles Bibliográficos
Autores principales:	Carvalho, Magda Oliveira Seixas, Souza, André Luís Carvalho Santos, Carvalho, Mauricio Batista, Pacheco, Ana Paula Almeida Souza, Rocha, Larissa Carneiro, do Nascimento, Valma Maria Lopes, Figueiredo, Camylla Vilas Boas, Guarda, Caroline Conceição, Santiago, Rayra Pereira, Adekile, Adekunle, Goncalves, Marilda de Souza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681845/ https://www.ncbi.nlm.nih.gov/pubmed/29163550 http://dx.doi.org/10.3389/fimmu.2017.01491

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