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Impairment of Hepcidin Upregulation by Lipopolysaccharide in the Interleukin-6 Knockout Mouse Brain
To find out whether the Interleukin-6 (IL-6)/signal transducer and activator of transcription 3 (STAT3) signaling pathway is involved in the expression of hepcidin in the mouse brain in vivo, we investigated the phosphorylation of STAT3, as well as the expression of hepcidin mRNA, ferroportin 1 (Fpn...
Autores principales: | Zhang, Fa-Li, Hou, Hui-Min, Yin, Zhi-Nan, Chang, Lan, Li, Fe-Mi, Chen, Y.-J., Ke, Ya, Qian, Zhong-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681933/ https://www.ncbi.nlm.nih.gov/pubmed/29163042 http://dx.doi.org/10.3389/fnmol.2017.00367 |
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