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The Human Antimicrobial Peptides Dermcidin and LL-37 Show Novel Distinct Pathways in Membrane Interactions

Mammals protect themselves from inflammation triggered by microorganisms through secretion of antimicrobial peptides (AMPs). One mechanism by which AMPs kill bacterial cells is perforating their membranes. Membrane interactions and pore formation were investigated for α-helical AMPs leading to the f...

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Detalles Bibliográficos
Autores principales: Zeth, Kornelius, Sancho-Vaello, Enea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681987/
https://www.ncbi.nlm.nih.gov/pubmed/29164103
http://dx.doi.org/10.3389/fchem.2017.00086