Cargando…

Characterization of the leukemogenic potential of distal cytoplasmic CSF3R truncation and missense mutations

An increasing number of variants of unknown significance (VUS) are being identified in leukemia patients with the application of deep sequencing and these include CSF3R cytoplasmic mutations. Previous studies have demonstrated oncogenic potential of certain CSF3R truncation mutations prior to intern...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Haijiao, Schultz, Anna Reister, Luty, Samuel, Rofelty, Angela, Su, Yulong, Means, Sophie, Bottomly, Daniel, Wilmot, Beth, McWeeney, Shannon K., Tyner, Jeffrey W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682244/
https://www.ncbi.nlm.nih.gov/pubmed/28439110
http://dx.doi.org/10.1038/leu.2017.126