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Characterization of the leukemogenic potential of distal cytoplasmic CSF3R truncation and missense mutations
An increasing number of variants of unknown significance (VUS) are being identified in leukemia patients with the application of deep sequencing and these include CSF3R cytoplasmic mutations. Previous studies have demonstrated oncogenic potential of certain CSF3R truncation mutations prior to intern...
Autores principales: | Zhang, Haijiao, Schultz, Anna Reister, Luty, Samuel, Rofelty, Angela, Su, Yulong, Means, Sophie, Bottomly, Daniel, Wilmot, Beth, McWeeney, Shannon K., Tyner, Jeffrey W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682244/ https://www.ncbi.nlm.nih.gov/pubmed/28439110 http://dx.doi.org/10.1038/leu.2017.126 |
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