The vaccinia virus DNA polymerase structure provides insights into the mode of processivity factor binding

Vaccinia virus (VACV), the prototype member of the Poxviridae, replicates in the cytoplasm of an infected cell. The catalytic subunit of the DNA polymerase E9 binds the heterodimeric processivity factor A20/D4 to form the functional polymerase holoenzyme. Here we present the crystal structure of ful...

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Detalles Bibliográficos
Autores principales: Tarbouriech, Nicolas, Ducournau, Corinne, Hutin, Stephanie, Mas, Philippe J., Man, Petr, Forest, Eric, Hart, Darren J., Peyrefitte, Christophe N., Burmeister, Wim P., Iseni, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682278/
https://www.ncbi.nlm.nih.gov/pubmed/29129932
http://dx.doi.org/10.1038/s41467-017-01542-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682278/
https://www.ncbi.nlm.nih.gov/pubmed/29129932
http://dx.doi.org/10.1038/s41467-017-01542-z

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