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Dengue virus-reactive CD8(+) T cells mediate cross-protection against subsequent Zika virus challenge

Zika virus (ZIKV) and dengue virus (DENV) are antigenically related flaviviruses that share cross-reactivity in antibody and T cell responses, and co-circulate in increasing numbers of countries. Whether pre-existing DENV immunity can cross-protect or enhance ZIKV infection during sequential infecti...

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Detalles Bibliográficos
Autores principales: Wen, Jinsheng, Elong Ngono, Annie, Regla-Nava, Jose Angel, Kim, Kenneth, Gorman, Matthew J., Diamond, Michael S., Shresta, Sujan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682281/
https://www.ncbi.nlm.nih.gov/pubmed/29129917
http://dx.doi.org/10.1038/s41467-017-01669-z

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