Cargando…

TRIM24 is an oncogenic transcriptional co-activator of STAT3 in glioblastoma

Aberrant amplification and mutations of epidermal growth factor receptor (EGFR) are the most common oncogenic events in glioblastoma (GBM), but the mechanisms by which they promote aggressive pathogenesis are not well understood. Here, we determine that non-canonical histone signature acetylated H3...

Descripción completa

Detalles Bibliográficos
Autores principales: Lv, Deguan, Li, Yanxin, Zhang, Weiwei, Alvarez, Angel A., Song, Lina, Tang, Jianming, Gao, Wei-Qiang, Hu, Bo, Cheng, Shi-Yuan, Feng, Haizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682287/
https://www.ncbi.nlm.nih.gov/pubmed/29129908
http://dx.doi.org/10.1038/s41467-017-01731-w