RNA editing by ADAR1 leads to context-dependent transcriptome-wide changes in RNA secondary structure

Adenosine deaminase acting on RNA 1 (ADAR1) is the master RNA editor, catalyzing the deamination of adenosine to inosine. RNA editing is vital for preventing abnormal activation of cytosolic nucleic acid sensing pathways by self-double-stranded RNAs. Here we determine, by parallel analysis of RNA se...

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Detalles Bibliográficos
Autores principales: Solomon, Oz, Di Segni, Ayelet, Cesarkas, Karen, Porath, Hagit T., Marcu-Malina, Victoria, Mizrahi, Orel, Stern-Ginossar, Noam, Kol, Nitzan, Farage-Barhom, Sarit, Glick-Saar, Efrat, Lerenthal, Yaniv, Levanon, Erez Y., Amariglio, Ninette, Unger, Ron, Goldstein, Itamar, Eyal, Eran, Rechavi, Gidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682290/
https://www.ncbi.nlm.nih.gov/pubmed/29129909
http://dx.doi.org/10.1038/s41467-017-01458-8

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