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Inhibition of Allograft Inflammatory Factor-1 in Dendritic Cells Restrains CD4(+) T Cell Effector Responses and Induces CD25(+)Foxp3(+) T Regulatory Subsets

Allograft inflammatory factor-1 (AIF1) is a cytoplasmic scaffold protein shown to influence immune responses in macrophages and microglial cells. The protein contains Ca(2+) binding EF-hand and PDZ interaction domains important for mediating intracellular signaling complexes. This study now reports...

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Detalles Bibliográficos
Autores principales:	Elizondo, Diana M., Andargie, Temesgen E., Yang, Dazhi, Kacsinta, Apollo D., Lipscomb, Michael W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682305/ https://www.ncbi.nlm.nih.gov/pubmed/29167673 http://dx.doi.org/10.3389/fimmu.2017.01502

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