HSF4 regulates lens fiber cell differentiation by activating p53 and its downstream regulators

Cataract refers to opacities of the lens that impede the passage of light. Mutations in heat shock transcription factor 4 (HSF4) have been associated with cataract; however, the mechanisms regarding how mutations in HSF4 cause cataract are still obscure. In this study, we generated an hsf4 knockout...

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Detalles Bibliográficos
Autores principales: Gao, Meng, Huang, Yuwen, Wang, Ling, Huang, Mi, Liu, Fei, Liao, Shengjie, Yu, Shanshan, Lu, Zhaojing, Han, Shanshan, Hu, Xuebin, Qu, Zhen, Liu, Xiliang, Assefa Yimer, Tinsae, Yang, Lifang, Tang, Zhaohui, Li, David Wan-Cheng, Liu, Mugen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682647/
https://www.ncbi.nlm.nih.gov/pubmed/28981088
http://dx.doi.org/10.1038/cddis.2017.478

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