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Engineered fibroblast growth factor 19 protects from acetaminophen-induced liver injury and stimulates aged liver regeneration in mice
The liver displays a remarkable regenerative capacity triggered upon tissue injury or resection. However, liver regeneration can be overwhelmed by excessive parenchymal destruction or diminished by pre-existing conditions hampering repair. Fibroblast growth factor 19 (FGF19, rodent FGF15) is an ente...
Autores principales: | Alvarez-Sola, Gloria, Uriarte, Iker, Latasa, Maria U, Jimenez, Maddalen, Barcena-Varela, Marina, Santamaría, Eva, Urtasun, Raquel, Rodriguez-Ortigosa, Carlos, Prieto, Jesús, Corrales, Fernando J, Baulies, Anna, García-Ruiz, Carmen, Fernandez-Checa, Jose C, Berraondo, Pedro, Fernandez-Barrena, Maite G, Berasain, Carmen, Avila, Matías A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682649/ https://www.ncbi.nlm.nih.gov/pubmed/28981086 http://dx.doi.org/10.1038/cddis.2017.480 |
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