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ANP promotes proliferation and inhibits apoptosis of ovarian granulosa cells by NPRA/PGRMC1/EGFR complex and improves ovary functions of PCOS rats

Polycystic ovary syndrome (PCOS) is a complicated reproductive endocrine disease characterized by polycystic ovaries, hyperandrogenism and anovulation. It is one of the main causes of infertility. RU486 is an antagonist of progesterone receptor, and most commonly used as a contraceptive. However, wh...

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Detalles Bibliográficos
Autores principales: Zheng, Qin, Li, Yulin, Zhang, Dandan, Cui, Xinyuan, Dai, Kuixing, Yang, Yu, Liu, Shuai, Tan, Jichun, Yan, Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682660/
https://www.ncbi.nlm.nih.gov/pubmed/29072679
http://dx.doi.org/10.1038/cddis.2017.494