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ANP promotes proliferation and inhibits apoptosis of ovarian granulosa cells by NPRA/PGRMC1/EGFR complex and improves ovary functions of PCOS rats
Polycystic ovary syndrome (PCOS) is a complicated reproductive endocrine disease characterized by polycystic ovaries, hyperandrogenism and anovulation. It is one of the main causes of infertility. RU486 is an antagonist of progesterone receptor, and most commonly used as a contraceptive. However, wh...
Autores principales: | Zheng, Qin, Li, Yulin, Zhang, Dandan, Cui, Xinyuan, Dai, Kuixing, Yang, Yu, Liu, Shuai, Tan, Jichun, Yan, Qiu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682660/ https://www.ncbi.nlm.nih.gov/pubmed/29072679 http://dx.doi.org/10.1038/cddis.2017.494 |
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