A novel acridine derivative, LS-1-10 inhibits autophagic degradation and triggers apoptosis in colon cancer cells

Autophagy promotes cancer cell survival and drug resistance by degrading harmful cellular components and maintaining cellular energy levels. Disruption of autophagy may be a promising approach to sensitize cancer cells to anticancer drugs. The combination of autophagic inhibitors, such as chloroquin...

Descripción completa

Detalles Bibliográficos
Autores principales: Fu, Wan, Li, Xue, Lu, Xiaopeng, Zhang, Luyao, Li, Ran, Zhang, Nan, Liu, Shan, Yang, Xin, Wang, Yue, Zhao, Ying, Meng, Xiangbao, Zhu, Wei-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682664/
https://www.ncbi.nlm.nih.gov/pubmed/28981103
http://dx.doi.org/10.1038/cddis.2017.498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682664/
https://www.ncbi.nlm.nih.gov/pubmed/28981103
http://dx.doi.org/10.1038/cddis.2017.498

Ejemplares similares