Cooperation of Rel family members in regulating Aβ(1-40)-mediated pro-inflammatory cytokine secretion by retinal pigment epithelial cells

Amyloid-beta (Aβ) is a hallmark component of age-related macular degeneration (AMD), which induces secretion of pro-inflammatory cytokines from retinal pigment epithelium (RPE). Previous studies have shown that p50/RelA (p65), a member of NF-κB family, is an essential pro-inflammatory transcription...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Junran, Huang, Peirong, Liang, Jian, Li, Jie, Shen, Mengxi, She, Xiangjun, Feng, Yiji, Luo, Xueting, Liu, Te, Sun, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682668/
https://www.ncbi.nlm.nih.gov/pubmed/29022897
http://dx.doi.org/10.1038/cddis.2017.502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682668/
https://www.ncbi.nlm.nih.gov/pubmed/29022897
http://dx.doi.org/10.1038/cddis.2017.502

Ejemplares similares