Cargando…

Cooperation of Rel family members in regulating Aβ(1-40)-mediated pro-inflammatory cytokine secretion by retinal pigment epithelial cells

Amyloid-beta (Aβ) is a hallmark component of age-related macular degeneration (AMD), which induces secretion of pro-inflammatory cytokines from retinal pigment epithelium (RPE). Previous studies have shown that p50/RelA (p65), a member of NF-κB family, is an essential pro-inflammatory transcription...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Junran, Huang, Peirong, Liang, Jian, Li, Jie, Shen, Mengxi, She, Xiangjun, Feng, Yiji, Luo, Xueting, Liu, Te, Sun, Xiaodong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682668/ https://www.ncbi.nlm.nih.gov/pubmed/29022897 http://dx.doi.org/10.1038/cddis.2017.502

Ejemplares similares

Photosensitization of A2E triggers telomere dysfunction and accelerates retinal pigment epithelium senescence
por: Wang, Jing, et al.
Publicado: (2018)

Choroidal pericytes promote subretinal fibrosis after experimental photocoagulation
por: Luo, Xueting, et al.
Publicado: (2018)

ROS production and mitochondrial dysfunction driven by PU.1-regulated NOX4-p22(phox) activation in Aβ-induced retinal pigment epithelial cell injury
por: Sun, Junran, et al.
Publicado: (2020)

Cell transformation by v-Rel reveals distinct roles of AP-1 family members in Rel/NF-κB oncogenesis
por: Liss, Andrew S., et al.
Publicado: (2010)

NF-κB/Rel Transcription Factors in Pancreatic Cancer: Focusing on RelA, c-Rel, and RelB
por: Kabacaoglu, Derya, et al.
Publicado: (2019)

Requirement for the NF-κB Family Member RelA in the Development of Secondary Lymphoid Organs
por: Alcamo, Elizabeth, et al.
Publicado: (2002)

RelB contributes to the survival, migration and lymphomagenesis of B cells with constitutively active CD40 signaling
por: Kuhn, Laura B., et al.
Publicado: (2022)

RelB and Neuroinflammation
por: Mockenhaupt, Karli, et al.
Publicado: (2021)

Prognostic impact of c-Rel nuclear expression and REL amplification and crosstalk between c-Rel and the p53 pathway in diffuse large B-cell lymphoma
por: Li, Ling, et al.
Publicado: (2015)

Differential Requirement for Rel/Nuclear Factor κB Family Members in Natural Killer T Cell Development
por: Sivakumar, Vallabhapurapu, et al.
Publicado: (2003)

RelB promotes liver fibrosis via inducing the release of injury‐associated inflammatory cytokines
por: Zhou, Danhua, et al.
Publicado: (2020)

Pro-survival and anti-inflammatory roles of NF-κB c-Rel in the Parkinson's disease models
por: Wang, Zishan, et al.
Publicado: (2020)

RelB and RelE of Escherichia coli Form a Tight Complex That Represses Transcription via the Ribbon–Helix–Helix Motif in RelB
por: Overgaard, Martin, et al.
Publicado: (2009)

The Crystal Structure of the Intact E. coli RelBE Toxin-Antitoxin Complex Provides the Structural Basis for Conditional Cooperativity
por: Bøggild, Andreas, et al.
Publicado: (2012)

Structural and mechanistic divergence of the small (p)ppGpp synthetases RelP and RelQ
por: Steinchen, Wieland, et al.
Publicado: (2018)

The structure of DarB in complex with Rel(NTD) reveals nonribosomal activation of Rel stringent factors
por: Ainelo, Andres, et al.
Publicado: (2023)

METTL3-mediated m(6)A modification of HMGA2 mRNA promotes subretinal fibrosis and epithelial–mesenchymal transition
por: Wang, Yuwei, et al.
Publicado: (2023)

Growth of nonexudative macular neovascularization in age-related macular degeneration: an indicator of biological lesion activity
por: Wang, Yusong, et al.
Publicado: (2022)

S5.3d How mitochondrial complex I proteins in Candida albicans moderate phagocytosis and the production of pro-inflammatory cytokines in murine macrophages and dendritic cells
por: She, Xiaodong, et al.
Publicado: (2022)

NLRP3 Blockade Suppresses Pro-Inflammatory and Pro-Angiogenic Cytokine Secretion in Diabetic Retinopathy
por: Chai, Guangrui, et al.
Publicado: (2020)

Subinhibitory Concentrations of Bacteriostatic Antibiotics Induce relA-Dependent and relA-Independent Tolerance to β-Lactams
por: Kudrin, Pavel, et al.
Publicado: (2017)

Velvet Family Members Regulate Pigment Synthesis of the Fruiting Bodies of Auricularia cornea
por: Ma, Xiaoxu, et al.
Publicado: (2023)

Forkhead Transcription Factor FOXP3 Upregulates CD25 Expression through Cooperation with RelA/NF-κB
por: Camperio, Cristina, et al.
Publicado: (2012)

REL, a member of the NF-κB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis
por: Gregersen, Peter K., et al.
Publicado: (2009)

RelAp43, a Member of the NF-κB Family Involved in Innate Immune Response against Lyssavirus Infection
por: Luco, Sophie, et al.
Publicado: (2012)

40 ans de coopération CERN-Saclay
Publicado: (2003)

BHLHE40 confers a pro-survival and pro-metastatic phenotype to breast cancer cells by modulating HBEGF secretion
por: Sethuraman, Aarti, et al.
Publicado: (2018)

The Role of relA and spoT in Yersinia pestis KIM5(+) Pathogenicity
por: Sun, Wei, et al.
Publicado: (2009)

Depletion of c-Rel from Cytokine Gene Promoters Is Required for Chromatin Reassembly and Termination of Gene Responses to T Cell Activation
por: Poke, Fiona S., et al.
Publicado: (2012)

SPSC - 2nd list of members - 40
por: CERN. Geneva. SPS Experiments Committee
Publicado: (1984)

Differential RelA- and RelB-dependent gene transcription in LTβR-stimulated mouse embryonic fibroblasts
por: Lovas, Agnes, et al.
Publicado: (2008)

ATF5 Attenuates the Secretion of Pro-Inflammatory Cytokines in Activated Microglia
por: Zhu, Jiebo, et al.
Publicado: (2023)

Clinical Application of Cytokines in Cancer Immunotherapy
por: Qiu, Yi, et al.
Publicado: (2021)

Borrelia [bә-rel′e-ә]
Publicado: (2009)

Influence of the relA gene on ribosome frameshifting
por: Masucci, J., et al.
Publicado: (2002)

Roles of Pro- and Anti-Inflammatory Cytokines in the Pathogenesis of SLE
por: Su, Ding-Lei, et al.
Publicado: (2012)

Identification of genes responsible for RelA-dependent proliferation arrest in human mammary epithelial cells conditionally expressing RelA
por: Kochupurakkal, Bose S., et al.
Publicado: (2015)

Biochemical and X-ray analyses of the players involved in the faRel2/aTfaRel2 toxin–antitoxin operon
por: Dominguez-Molina, Lucia, et al.
Publicado: (2023)

Pigment epithelium-derived factor reduces apoptosis and pro-inflammatory cytokine gene expression in a murine model of focal retinal degeneration
por: Wang, Yujuan, et al.
Publicado: (2013)

The pro-apoptotic Bcl-2 family member tBid localizes to mitochondrial contact sites
por: Lutter, Michael, et al.
Publicado: (2001)

Cannot write session to /tmp/vufind_sessions/sess_7csdlsqi5cugiij8grdabav8ge