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iASPP facilitates tumor growth by promoting mTOR-dependent autophagy in human non-small-cell lung cancer
Autophagy serves a critical function in the pathogenesis, response to therapy and clinical outcome in cancers. Although a recent report showed a role of iASPP in suppressing autophagy, its potential activity as a regulator of autophagy has not been investigated in lung cancer. Here we investigated t...
Autores principales: | Xue, Yijun, Han, Haibo, Wu, Lina, Pan, Bo, Dong, Bin, Yin, C Cameron, Tian, Zhihua, Liu, Xijuan, Yang, Yue, Zhang, Hong, Chen, Yingyu, Chen, Jinfeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682680/ https://www.ncbi.nlm.nih.gov/pubmed/29072696 http://dx.doi.org/10.1038/cddis.2017.515 |
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