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Caspase-2 deficiency enhances whole-body carbohydrate utilisation and prevents high-fat diet-induced obesity

Caspase-2 has been shown to be involved in metabolic homeostasis. Here, we show that caspase-2 deficiency alters basal energy metabolism by shifting the balance in fuel choice from fatty acid to carbohydrate usage. At 4 weeks of age, whole-body carbohydrate utilisation was increased in Casp2(−/−) mi...

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Detalles Bibliográficos
Autores principales:	Wilson, Claire H, Nikolic, Andrej, Kentish, Stephen J, Keller, Marianne, Hatzinikolas, George, Dorstyn, Loretta, Page, Amanda J, Kumar, Sharad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682682/ https://www.ncbi.nlm.nih.gov/pubmed/29072701 http://dx.doi.org/10.1038/cddis.2017.518

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