c-Abl-mediated Drp1 phosphorylation promotes oxidative stress-induced mitochondrial fragmentation and neuronal cell death

Oxidative stress-induced mitochondrial dysfunction and neuronal cell death have important roles in the development of neurodegenerative diseases. Dynamin related protein 1 (Drp1) is a critical factor in regulating mitochondrial dynamics. A variety of posttranslational modifications of Drp1 have been...

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Detalles Bibliográficos
Autores principales: Zhou, Lujun, Zhang, Qiang, Zhang, Peng, Sun, Lei, Peng, Can, Yuan, Zengqiang, Cheng, Jinbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682686/
https://www.ncbi.nlm.nih.gov/pubmed/29022905
http://dx.doi.org/10.1038/cddis.2017.524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682686/
https://www.ncbi.nlm.nih.gov/pubmed/29022905
http://dx.doi.org/10.1038/cddis.2017.524

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