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Differential regulation of spermatogenic process by Lkb1 isoforms in mouse testis
Liver serine/threonine kinase B1 (LKB1) is a tumor suppressor associated with the pathogenesis of Peutz-Jeghers syndrome. Affected males are at increased risk of developing Sertoli cell tumors and display defective spermatogenesis. Male mice lacking the short isoform (Lkb1(S)) of Lkb1 were sterile a...
Autores principales: | Kong, Feifei, Wang, Mei, Huang, Xiaojing, Yue, Qiuling, Wei, Xiang, Dou, Xiaowei, Peng, Xiaoxu, Jia, Yuanyuan, Zheng, Ke, Wu, Tinghe, Yan, Jun, Li, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682689/ https://www.ncbi.nlm.nih.gov/pubmed/29022902 http://dx.doi.org/10.1038/cddis.2017.527 |
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