Optical Coherence Tomography and Subclinical Optical Neuritis in Longitudinally Extensive Transverse Myelitis

OBJECTIVE: The aim is to compare the retinal nerve fiber layer (RNFL) thickness of longitudinally extensive transverse myelitis (LETM) eyes without previous optic neuritis with that of healthy control subjects. METHODS: Over 20 LETM eyes and 20 normal control eyes were included in the study and subj...

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Detalles Bibliográficos
Autores principales: Sinha, Prakash Kumar, Joshi, Deepika, Singh, Virendra Pratap, Deshmukh, Sujit, Singh, Usha, Pathak, Abhishek, Mishra, Vijay Nath, Chaurasia, Rameshwar Nath, Sharda, Vivek, Gupta, Garima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682738/
https://www.ncbi.nlm.nih.gov/pubmed/29184337
http://dx.doi.org/10.4103/aian.AIAN_170_17
Descripción
Sumario:OBJECTIVE: The aim is to compare the retinal nerve fiber layer (RNFL) thickness of longitudinally extensive transverse myelitis (LETM) eyes without previous optic neuritis with that of healthy control subjects. METHODS: Over 20 LETM eyes and 20 normal control eyes were included in the study and subjected to optical coherence tomography to evaluate and compare the RNFL thickness. RESULT: Significant RNFL thinning was observed at 8 o'clock position in LETM eyes as compared to the control eyes (P = 0.038). No significant differences were seen in other RNFL measurements. CONCLUSION: Even in the absence of previous optic neuritis LETM can lead to subclinical axonal damage leading to focal RNFL thinning.

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