Cargando…
PMK-1 p38 MAPK promotes cadmium stress resistance, the expression of SKN-1/Nrf and DAF-16 target genes, and protein biosynthesis in Caenorhabditis elegans
The mechanisms of cadmium (Cd) resistance are complex and not sufficiently understood. The present study, therefore, aimed at assessing the roles of important components of stress-signaling pathways and of ABC transporters under severe Cd stress in Caenorhabditis elegans. Survival assays on mutant a...
Autores principales: | Keshet, Alex, Mertenskötter, Ansgar, Winter, Sarah A., Brinkmann, Vanessa, Dölling, Ramona, Paul, Rüdiger J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682872/ https://www.ncbi.nlm.nih.gov/pubmed/28766017 http://dx.doi.org/10.1007/s00438-017-1351-z |
Ejemplares similares
-
Loss of muscleblind splicing factor shortens Caenorhabditis elegans lifespan by reducing the activity of p38 MAPK/PMK-1 and transcription factors ATF-7 and Nrf/SKN-1
por: Matilainen, Olli, et al.
Publicado: (2021) -
Catalpol Modulates Lifespan via DAF-16/FOXO and SKN-1/Nrf2 Activation in Caenorhabditis elegans
por: Seo, Hyun Won, et al.
Publicado: (2015) -
The p38 MAPK/PMK-1 Pathway Is Required for Resistance to Nocardia farcinica Infection in Caenorhabditis elegance
por: Yang, Ruiqiu, et al.
Publicado: (2022) -
SKN-1 Is a Negative Regulator of DAF-16 and Somatic Stress Resistance in Caenorhabditis elegans
por: Deng, Jianhui, et al.
Publicado: (2020) -
Pioglitazone Hydrochloride Extends the Lifespan of Caenorhabditis elegans by Activating DAF-16/FOXO- and SKN-1/NRF2-Related Signaling Pathways
por: Jia, Wenjuan, et al.
Publicado: (2022)