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Chromatin-enriched lncRNAs can act as cell-type specific activators of proximal gene transcription

We recently described a new class of long noncoding RNA defined by especially tight chromatin association, whose presence is strongly correlated with expression of nearby genes in HEK293 cells. Here we critically examine the generality and cis-enhancer mechanism of this class of chromatin enriched R...

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Detalles Bibliográficos
Autores principales: Werner, Michael S., Sullivan, Matthew A., Shah, Rohan N., Nadadur, Rangarajan D., Grzybowski, Adrian T., Galat, Vasiliy, Moskowitz, Ivan P., Ruthenburg, Alexander J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682930/
https://www.ncbi.nlm.nih.gov/pubmed/28628087
http://dx.doi.org/10.1038/nsmb.3424