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Chromatin-enriched lncRNAs can act as cell-type specific activators of proximal gene transcription
We recently described a new class of long noncoding RNA defined by especially tight chromatin association, whose presence is strongly correlated with expression of nearby genes in HEK293 cells. Here we critically examine the generality and cis-enhancer mechanism of this class of chromatin enriched R...
Autores principales: | Werner, Michael S., Sullivan, Matthew A., Shah, Rohan N., Nadadur, Rangarajan D., Grzybowski, Adrian T., Galat, Vasiliy, Moskowitz, Ivan P., Ruthenburg, Alexander J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682930/ https://www.ncbi.nlm.nih.gov/pubmed/28628087 http://dx.doi.org/10.1038/nsmb.3424 |
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