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Psoriasis in children
The clinical presentation, disease associations, and diverse treatment modalities in overcoming the challenges of managing pediatric psoriasis have been extensively summarized in this article. An extensive literature review revealed the differences in presentation of psoriasis during infancy, childh...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683121/ https://www.ncbi.nlm.nih.gov/pubmed/29387599 http://dx.doi.org/10.2147/PTT.S87650 |
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author | Pinson, Roxanne Sotoodian, Bahman Fiorillo, Loretta |
author_facet | Pinson, Roxanne Sotoodian, Bahman Fiorillo, Loretta |
author_sort | Pinson, Roxanne |
collection | PubMed |
description | The clinical presentation, disease associations, and diverse treatment modalities in overcoming the challenges of managing pediatric psoriasis have been extensively summarized in this article. An extensive literature review revealed the differences in presentation of psoriasis during infancy, childhood, and adolescence. We also summarized the latest topical, systemic, and biological modalities in treating recalcitrant psoriasis. The association of psoriasis with juvenile arthritis and obesity and the significant influence of the disease on the children’s quality of life were explored. The clinical presentation of psoriasis can evolve during the child’s lifespan. While many treatment modalities already exist for treating pediatric psoriasis, some of the new biologics that are approved for adult patients have not been investigated in the pediatric population and no algorithm exists for their use in this population. Large clinical studies in the future will enhance our understanding with regards to their safety and potential implications in pediatric populations. |
format | Online Article Text |
id | pubmed-5683121 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-56831212018-01-31 Psoriasis in children Pinson, Roxanne Sotoodian, Bahman Fiorillo, Loretta Psoriasis (Auckl) Review The clinical presentation, disease associations, and diverse treatment modalities in overcoming the challenges of managing pediatric psoriasis have been extensively summarized in this article. An extensive literature review revealed the differences in presentation of psoriasis during infancy, childhood, and adolescence. We also summarized the latest topical, systemic, and biological modalities in treating recalcitrant psoriasis. The association of psoriasis with juvenile arthritis and obesity and the significant influence of the disease on the children’s quality of life were explored. The clinical presentation of psoriasis can evolve during the child’s lifespan. While many treatment modalities already exist for treating pediatric psoriasis, some of the new biologics that are approved for adult patients have not been investigated in the pediatric population and no algorithm exists for their use in this population. Large clinical studies in the future will enhance our understanding with regards to their safety and potential implications in pediatric populations. Dove Medical Press 2016-10-20 /pmc/articles/PMC5683121/ /pubmed/29387599 http://dx.doi.org/10.2147/PTT.S87650 Text en © 2016 Pinson et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Review Pinson, Roxanne Sotoodian, Bahman Fiorillo, Loretta Psoriasis in children |
title | Psoriasis in children |
title_full | Psoriasis in children |
title_fullStr | Psoriasis in children |
title_full_unstemmed | Psoriasis in children |
title_short | Psoriasis in children |
title_sort | psoriasis in children |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683121/ https://www.ncbi.nlm.nih.gov/pubmed/29387599 http://dx.doi.org/10.2147/PTT.S87650 |
work_keys_str_mv | AT pinsonroxanne psoriasisinchildren AT sotoodianbahman psoriasisinchildren AT fiorilloloretta psoriasisinchildren |