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Prokaryotic expression and characterization of the heterodimeric construction of ZnT8 and its application for autoantibodies detection in diabetes mellitus

BACKGROUND: In the present work we described the recombinant production and characterization of heterodimeric construction ZnT8-Arg-Trp325 fused to thioredoxin using a high-performance expression system such as Escherichia coli. In addition, we apply this novel recombinant antigen in a non-radiometr...

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Detalles Bibliográficos
Autores principales:	Faccinetti, Natalia I., Guerra, Luciano L., Sabljic, Adriana V., Bombicino, Silvina S., Rovitto, Bruno D., Iacono, Ruben F., Poskus, Edgardo, Trabucchi, Aldana, Valdez, Silvina N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683521/ https://www.ncbi.nlm.nih.gov/pubmed/29132366 http://dx.doi.org/10.1186/s12934-017-0816-4

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