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Kinase profiling of liposarcomas using RNAi and drug screening assays identified druggable targets
BACKGROUND: Liposarcoma, the most common soft tissue tumor, is understudied cancer, and limited progress has been made in the treatment of metastatic disease. The Achilles heel of cancer often is their kinases that are excellent therapeutic targets. However, very limited knowledge exists of therapeu...
Autores principales: | Kanojia, Deepika, Garg, Manoj, Martinez, Jacqueline, M.T., Anand, Luty, Samuel B., Doan, Ngan B., Said, Jonathan W., Forscher, Charles, Tyner, Jeffrey W., Koeffler, H. Phillip |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683536/ https://www.ncbi.nlm.nih.gov/pubmed/29132397 http://dx.doi.org/10.1186/s13045-017-0540-x |
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