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Avian infectious bronchitis virus disrupts the melanoma differentiation associated gene 5 (MDA5) signaling pathway by cleavage of the adaptor protein MAVS

BACKGROUND: Melanoma differentiation associated gene 5 (MDA5) and retinoic acid-inducible gene-I (RIG-I) selectively sense cytoplasmic viral RNA to induce an antiviral immune response. Infectious bronchitis virus (IBV) is one of the most important infectious agents in chickens, and in chicken cells,...

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Detalles Bibliográficos
Autores principales:	Yu, Liping, Zhang, Xiaorong, Wu, Tianqi, Su, Jin, Wang, Yuyang, Wang, Yuexin, Ruan, Baoyang, Niu, Xiaosai, Wu, Yantao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683607/ https://www.ncbi.nlm.nih.gov/pubmed/29132350 http://dx.doi.org/10.1186/s12917-017-1253-7

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