Cargando…

Loss of the Caenorhabditis elegans pocket protein LIN-35 reveals MuvB's innate function as the repressor of DREAM target genes

The DREAM (Dp/Retinoblastoma(Rb)-like/E2F/MuvB) transcriptional repressor complex acts as a gatekeeper of the mammalian cell cycle by establishing and maintaining cellular quiescence. How DREAM’s three functional components, the E2F-DP heterodimer, the Rb-like pocket protein, and the MuvB subcomplex...

Descripción completa

Detalles Bibliográficos
Autores principales:	Goetsch, Paul D., Garrigues, Jacob M., Strome, Susan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683655/ https://www.ncbi.nlm.nih.gov/pubmed/29091720 http://dx.doi.org/10.1371/journal.pgen.1007088

Ejemplares similares

MuvB: A Key to Cell Cycle Control in Ovarian Cancer
por: Iness, Audra N., et al.
Publicado: (2018)

Structure of a nucleosome-bound MuvB transcription factor complex reveals DNA remodelling
por: Koliopoulos, Marios G., et al.
Publicado: (2022)

The MuvB complex safeguards embryonic stem cell identity through regulation of the cell cycle machinery
por: Wang, Congcong, et al.
Publicado: (2022)

Interaction of YAP with the Myb-MuvB (MMB) complex defines a transcriptional program to promote the proliferation of cardiomyocytes
por: Gründl, Marco, et al.
Publicado: (2020)

The MuvB complex binds and stabilizes nucleosomes downstream of the transcription start site of cell-cycle dependent genes
por: Asthana, Anushweta, et al.
Publicado: (2022)

Author Correction: Structure of a nucleosome-bound MuvB transcription factor complex reveals DNA remodelling
por: Koliopoulos, Marios G., et al.
Publicado: (2023)

A Cyclin A—Myb-MuvB—Aurora B network regulates the choice between mitotic cycles and polyploid endoreplication cycles
por: Rotelli, Michael D., et al.
Publicado: (2019)

A Network of Genes Antagonistic to the LIN-35 Retinoblastoma Protein of Caenorhabditis elegans
por: Polley, Stanley R. G., et al.
Publicado: (2012)

Central spindle proteins and mitotic kinesins are direct transcriptional targets of MuvB, B-MYB and FOXM1 in breast cancer cell lines and are potential targets for therapy
por: Wolter, Patrick, et al.
Publicado: (2017)

Wnt Signaling Drives Ectopic Gene Expression and Larval Arrest in the Absence of the Caenorhabditis elegans DREAM Repressor Complex
por: Cherian, Jerrin R., et al.
Publicado: (2019)

Loss of LIN-35, the Caenorhabditis elegans ortholog of the tumor suppressor p105Rb, results in enhanced RNA interference
por: Lehner, Ben, et al.
Publicado: (2006)

LIN-35 is necessary in both the soma and germline for preserving fertility in Caenorhabditis elegans under moderate temperature stress
por: Mikeworth, Brian P., et al.
Publicado: (2023)

Repression of Germline Genes in Caenorhabditis elegans Somatic Tissues by H3K9 Dimethylation of Their Promoters
por: Rechtsteiner, Andreas, et al.
Publicado: (2019)

Regulation of Gliogenesis by lin-32/Atoh1 in Caenorhabditis elegans
por: Zhang, Albert, et al.
Publicado: (2020)

Molecular lesions in alleles of the Caenorhabditis elegans lin-11 gene
por: Young, Adrie F., et al.
Publicado: (2022)

Diverse Chromatin Remodeling Genes Antagonize the Rb-Involved SynMuv Pathways in C. elegans
por: Cui, Mingxue, et al.
Publicado: (2006)

The lin-4 Gene Controls Fat Accumulation and Longevity in Caenorhabditis elegans
por: Zhu, Chun, et al.
Publicado: (2010)

An atonal homolog, lin-32, regulates hypodermal morphogenesis in Caenorhabditis elegans
por: Hori, Sayaka, et al.
Publicado: (2023)

A Mechanistic Basis for the Coordinated Regulation of Pharyngeal Morphogenesis in Caenorhabditis elegans by LIN-35/Rb and UBC-18–ARI-1
por: Mani, Kumaran, et al.
Publicado: (2009)

Suppressors, Screens, and Genes: An Educational Primer for Use with “A Network of Genes Antagonistic to the LIN-35 Retinoblastoma Protein of Caenorhabditis elegans”
por: De Stasio, Elizabeth A.
Publicado: (2012)

Modulation of Caenorhabditis elegans infection sensitivity by the LIN-7 cell junction protein
por: Sem, XiaoHui, et al.
Publicado: (2012)

LIN-12/Notch Regulates GABA Signaling at the Caenorhabditis elegans Neuromuscular Junction
por: Sorkaç, Altar, et al.
Publicado: (2018)

LIN-32/Atonal Controls Oxygen Sensing Neuron Development in Caenorhabditis elegans
por: Rojo Romanos, Teresa, et al.
Publicado: (2017)

The TRIM-NHL Protein LIN-41 Controls the Onset of Developmental Plasticity in Caenorhabditis elegans
por: Tocchini, Cristina, et al.
Publicado: (2014)

LIN-42, the Caenorhabditis elegans PERIOD homolog, Negatively Regulates MicroRNA Transcription
por: Perales, Roberto, et al.
Publicado: (2014)

Caenorhabditis elegans transposable elements harbor diverse transcription factor DNA-binding sites
por: Garrigues, Jacob M, et al.
Publicado: (2022)

The DREAM complex promotes gene body H2A.Z for target repression
por: Latorre, Isabel, et al.
Publicado: (2015)

Coordinated Regulation of Intestinal Functions in C. elegans by LIN-35/Rb and SLR-2
por: Kirienko, Natalia V., et al.
Publicado: (2008)

Defining heterochromatin in C. elegans through genome-wide analysis of the heterochromatin protein 1 homolog HPL-2
por: Garrigues, Jacob M., et al.
Publicado: (2015)

OSM-11 Facilitates LIN-12 Notch Signaling during Caenorhabditis elegans Vulval Development
por: Komatsu, Hidetoshi, et al.
Publicado: (2008)

p24 Proteins and Quality Control of LIN-12 and GLP-1 Trafficking in Caenorhabditis elegans
por: Wen, Chenhui, et al.
Publicado: (1999)

The conserved histone chaperone LIN‐53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans
por: Müthel, Stefanie, et al.
Publicado: (2019)

Remodeling of the Caenorhabditis elegans non-coding RNA transcriptome by heat shock
por: Schreiner, William P, et al.
Publicado: (2019)

Structural basis for LIN54 recognition of CHR elements in cell cycle-regulated promoters
por: Marceau, Aimee H., et al.
Publicado: (2016)

Caenorhabditis elegans chromosome arms are anchored to the nuclear membrane via discontinuous association with LEM-2
por: Ikegami, Kohta, et al.
Publicado: (2010)

The lin-35/Rb and RNAi pathways cooperate to regulate a key cell cycle transition in C. elegans
por: Ouellet, Jimmy, et al.
Publicado: (2007)

Lin-5 Is a Novel Component of the Spindle Apparatus Required for Chromosome Segregation and Cleavage Plane Specification in Caenorhabditis elegans
por: Lorson, Monique A., et al.
Publicado: (2000)

LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans
por: Lehrbach, Nicolas J., et al.
Publicado: (2009)

LIN-41 inactivation leads to delayed centrosome elimination and abnormal chromosome behavior during female meiosis in Caenorhabditis elegans
por: Matsuura, Rieko, et al.
Publicado: (2016)

Determinants in the LIN-12/Notch Intracellular Domain That Govern Its Activity and Stability During Caenorhabditis elegans Vulval Development
por: Deng, Yuting, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_kvbaru4lej47m73opfs1ighr23