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53BP1 and BRCA1 control pathway choice for stalled replication restart

The cellular pathways that restart stalled replication forks are essential for genome stability and tumor prevention. However, how many of these pathways exist in cells and how these pathways are selectively activated remain unclear. Here, we describe two major fork restart pathways, and demonstrate...

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Detalles Bibliográficos
Autores principales:	Xu, Yixi, Ning, Shaokai, Wei, Zheng, Xu, Ran, Xu, Xinlin, Xing, Mengtan, Guo, Rong, Xu, Dongyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2017
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683755/ https://www.ncbi.nlm.nih.gov/pubmed/29106372 http://dx.doi.org/10.7554/eLife.30523

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