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Adenocarcinoma arising from a gastric duplication cyst: a case report and literature review
INTRODUCTION: Alimentary tract cystic duplication is a rare congenital anomaly predominantly affecting females, and diagnosed mostly in the early years of life. CASE REPORT: We present here a case of a 51-year-old man presenting with a 2-day history of melena. Gastroscopy showed fresh blood, as well...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683793/ https://www.ncbi.nlm.nih.gov/pubmed/29158693 http://dx.doi.org/10.2147/IMCRJ.S138616 |
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author | Abdulla, Maheeba Abdulla Mohamed Al Saeed, Mahmood Ameer Alshaikh, Safa Nabar, Umesh J |
author_facet | Abdulla, Maheeba Abdulla Mohamed Al Saeed, Mahmood Ameer Alshaikh, Safa Nabar, Umesh J |
author_sort | Abdulla, Maheeba Abdulla Mohamed |
collection | PubMed |
description | INTRODUCTION: Alimentary tract cystic duplication is a rare congenital anomaly predominantly affecting females, and diagnosed mostly in the early years of life. CASE REPORT: We present here a case of a 51-year-old man presenting with a 2-day history of melena. Gastroscopy showed fresh blood, as well as a mass lesion and cavity at the fundus. Biopsies of the mass edge reported the occurrence of moderately differentiated adenocarcinoma and mild chronic gastritis. Computed tomography imaging showed a 5.1×6.5 cm cystic mass in the gastric greater curvature. The patient received six cycles of epirubicin, capecitabine, and oxaliplatin, followed by uncomplicated total gastrectomy. LITERATURE REVIEW: Data from all 11 reports of similar cases were reviewed and pooled. The result shows male predominance and variable symptoms, as well as a wide age range (25–76 years) at presentation. The cysts are commonly located along the greater curvature and are unilocular. Surgery was the treatment in most cases. CONCLUSION: Alimentary tract cystic duplication is rare and may predispose to malignancy. Early diagnosis and prompt surgical intervention is important for the best outcome. |
format | Online Article Text |
id | pubmed-5683793 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-56837932017-11-20 Adenocarcinoma arising from a gastric duplication cyst: a case report and literature review Abdulla, Maheeba Abdulla Mohamed Al Saeed, Mahmood Ameer Alshaikh, Safa Nabar, Umesh J Int Med Case Rep J Case Report INTRODUCTION: Alimentary tract cystic duplication is a rare congenital anomaly predominantly affecting females, and diagnosed mostly in the early years of life. CASE REPORT: We present here a case of a 51-year-old man presenting with a 2-day history of melena. Gastroscopy showed fresh blood, as well as a mass lesion and cavity at the fundus. Biopsies of the mass edge reported the occurrence of moderately differentiated adenocarcinoma and mild chronic gastritis. Computed tomography imaging showed a 5.1×6.5 cm cystic mass in the gastric greater curvature. The patient received six cycles of epirubicin, capecitabine, and oxaliplatin, followed by uncomplicated total gastrectomy. LITERATURE REVIEW: Data from all 11 reports of similar cases were reviewed and pooled. The result shows male predominance and variable symptoms, as well as a wide age range (25–76 years) at presentation. The cysts are commonly located along the greater curvature and are unilocular. Surgery was the treatment in most cases. CONCLUSION: Alimentary tract cystic duplication is rare and may predispose to malignancy. Early diagnosis and prompt surgical intervention is important for the best outcome. Dove Medical Press 2017-11-06 /pmc/articles/PMC5683793/ /pubmed/29158693 http://dx.doi.org/10.2147/IMCRJ.S138616 Text en © 2017 Abdulla et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Case Report Abdulla, Maheeba Abdulla Mohamed Al Saeed, Mahmood Ameer Alshaikh, Safa Nabar, Umesh J Adenocarcinoma arising from a gastric duplication cyst: a case report and literature review |
title | Adenocarcinoma arising from a gastric duplication cyst: a case report and literature review |
title_full | Adenocarcinoma arising from a gastric duplication cyst: a case report and literature review |
title_fullStr | Adenocarcinoma arising from a gastric duplication cyst: a case report and literature review |
title_full_unstemmed | Adenocarcinoma arising from a gastric duplication cyst: a case report and literature review |
title_short | Adenocarcinoma arising from a gastric duplication cyst: a case report and literature review |
title_sort | adenocarcinoma arising from a gastric duplication cyst: a case report and literature review |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683793/ https://www.ncbi.nlm.nih.gov/pubmed/29158693 http://dx.doi.org/10.2147/IMCRJ.S138616 |
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