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Caspase-2 mediates triglyceride (TG)-induced macrophage cell death

Triglyceride (TG) accumulation causes macrophage cell death, which affects the development of atherosclerosis. Here, we examined whether caspase-2 is implicated in TG-induced macrophage cell death. We found that caspase-2 activity is increased in TG-treated THP-1 macrophages, and that inhibition of...

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Detalles Bibliográficos
Autores principales:	Lim, Jaewon, Kim, Hyun-Kyung, Kim, Sung Hoon, Rhee, Ki-Jong, Kim, Yoon Suk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683820/ https://www.ncbi.nlm.nih.gov/pubmed/28768565 http://dx.doi.org/10.5483/BMBRep.2017.50.10.106

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