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B7-H1 Influences the Accumulation of Virus-Specific Tissue Resident Memory T Cells in the Central Nervous System

Therapies that target the PD-1/B7-H1 axis have revolutionized cancer treatment, yet precise knowledge of how this pathway provides benefit continues to evolve. Here, we report a novel role for the immune checkpoint ligand B7-H1 in the accumulation of tissue-resident memory CD8(+) T-cells (T(RM)). Af...

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Detalles Bibliográficos
Autores principales: Pavelko, Kevin D., Bell, Michael P., Harrington, Susan M., Dong, Haidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684101/
https://www.ncbi.nlm.nih.gov/pubmed/29170671
http://dx.doi.org/10.3389/fimmu.2017.01532

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