New melanocortin-like peptide of E. coli can suppress inflammation via the mammalian melanocortin-1 receptor (MC1R): possible endocrine-like function for microbes of the gut

E. coli releases a 33 amino acid peptide melanocortin-like peptide of E. coli (MECO-1) that is identical to the C-terminus of the E. coli elongation factor-G (EF-G) and has interesting similarities to two prominent mammalian melanocortin hormones, alpha-melanocyte-stimulating hormone (alpha-MSH) and...

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Detalles Bibliográficos
Autores principales: Qiang, Xiaoling, Liotta, Anthony S., Shiloach, Joseph, Gutierrez, J. C., Wang, Haichao, Ochani, Mahendar, Ochani, Kanta, Yang, Huan, Rabin, Aviva, LeRoith, Derek, Lesniak, Maxine A., Böhm, Markus, Maaser, Christian, Kannengiesser, Klaus, Donowitz, Mark, Rabizadeh, Shervin, Czura, Christopher J., Tracey, Kevin J., Westlake, Mark, Zarfeshani, Aida, Mehdi, Syed F., Danoff, Ann, Ge, Xueliang, Sanyal, Suparna, Schwartz, Gary J., Roth, Jesse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684143/
https://www.ncbi.nlm.nih.gov/pubmed/29152323
http://dx.doi.org/10.1038/s41522-017-0039-9

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