Role of MicroRNA-143 in Nerve Injury-Induced Upregulation of Dnmt3a Expression in Primary Sensory Neurons

Peripheral nerve injury increased the expression of the DNA methyltransferase 3A (Dnmt3a) mRNA and its encoding Dnmt3a protein in injured dorsal root ganglia (DRG). This increase is considered as an endogenous instigator in neuropathic pain genesis through epigenetic silencing of pain-associated gen...

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Detalles Bibliográficos
Autores principales: Xu, Bo, Cao, Jing, Zhang, Jun, Jia, Shushan, Wu, Shaogen, Mo, Kai, Wei, Guihua, Liang, Lingli, Miao, Xuerong, Bekker, Alex, Tao, Yuan-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684171/
https://www.ncbi.nlm.nih.gov/pubmed/29170626
http://dx.doi.org/10.3389/fnmol.2017.00350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684171/
https://www.ncbi.nlm.nih.gov/pubmed/29170626
http://dx.doi.org/10.3389/fnmol.2017.00350

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