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Role of MicroRNA-143 in Nerve Injury-Induced Upregulation of Dnmt3a Expression in Primary Sensory Neurons
Peripheral nerve injury increased the expression of the DNA methyltransferase 3A (Dnmt3a) mRNA and its encoding Dnmt3a protein in injured dorsal root ganglia (DRG). This increase is considered as an endogenous instigator in neuropathic pain genesis through epigenetic silencing of pain-associated gen...
Autores principales: | Xu, Bo, Cao, Jing, Zhang, Jun, Jia, Shushan, Wu, Shaogen, Mo, Kai, Wei, Guihua, Liang, Lingli, Miao, Xuerong, Bekker, Alex, Tao, Yuan-Xiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684171/ https://www.ncbi.nlm.nih.gov/pubmed/29170626 http://dx.doi.org/10.3389/fnmol.2017.00350 |
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